0501国际期刊速递丨今日热点血小板

TODAY今日发布HeartandVesselsEarlyRecent,Apr30,今日发布02篇ClinResCardiolEarlyRecent,Apr30,今日发布01篇JAMAEarlyRecent,Apr30,今日发布02篇HeartFailRevEarlyRecent,May01,今日发布02篇JIntervCardElectrophysiolEarlyRecent,May01,今日发布01篇RECOMMEND推荐阅读01年3月2日至4月21日Ad26.COV2.S疫苗接种后伴血小板减少的脑静脉窦血栓形成美国病例报告JAMAIsaacSee,JohnR.Su,etc.昨天23:05ImportanceCerebralvenoussinusthrombosis(CVST)withthrombocytopenia,arareandseriouscondition,hasbeendescribedinEuropefollowingreceiptoftheChAdOx1nCoV-19vaccine(Oxford/AstraZeneca),whichusesachimpanzeeadenoviralvector.Amechanismsimilartoautoimmuneheparin-inducedthrombocytopenia(HIT)hasbeenproposed.IntheUS,theAd26.COV2.SCOVID-19vaccine(Janssen/JohnsonallwereWhitewomen,reportedfrom11states.Sevenpatientshadatleast1CVSTriskfactor,includingobesity(n?=?6),hypothyroidism(n?=?1),andoralcontraceptiveuse(n?=?1);nonehaddocumentedpriorheparinexposure.TimefromAd26.COV2.Svaccinationtosymptomonsetrangedfrom6to15days.Elevenpatientsinitiallypresentedwithheadache;1patientinitiallypresentedwithbackpainandlaterdevelopedheadache.Ofthe12patientswithCVST,7alsohadintracerebralhemorrhage;8hadnon-CVSTthromboses.AfterdiagnosisofCVST,6patientsinitiallyreceivedheparintreatment.Plateletnadirrangedfrom9?×/μLto?×/μL.All11patientstestedfortheheparin-plateletfactor4HITantibodybyenzyme-linkedimmunosorbentassay(ELISA)screeninghadpositiveresults.Allpatientswerehospitalized(10inanintensivecareunit[ICU]).AsofApril21,,out

转载请注明：http://www.ctongt.com/gbzl/7935.html