冠状动脉疾病

冠状动脉支架置入术后支架内再狭窄的影响因


分析冠状动脉支架置入术后支架内再狭窄的影响因素,为临床预防再狭窄提供理论支持。

Toanalyzeinfluencingfactorsofin-stentrestenosisaftercoronaryarterystentimplantation,toprovidetheoreticalsupportforclinicalpreventionofrestenosis.

回顾性分析自年3月至年9月在我院行冠脉支架置入术,并于术后1年行冠脉造影随访的例患者的临床资料。以置入支架内径狭窄≥50%为再狭窄,分为再狭窄组(35例)和无再狭窄组(88例)。采用多因素Logistic回归分析分析冠脉支架内再狭窄的影响因素。

Clinicaldataofpatients,whoreceivedcoronaryarterystentimplantationinourhospitalfromMartoSepandreceivedcoronaryangiographyfollow-uponeyearafteroperation,wereretrospectivelyanalyzed.In-stentrestenosiswasregardedasstenosisofinnerdiameterofimplantedstent≥50%,sopatientsweredividedintorestenosisgroup(n=35)andnon-restenosisgroup(n=88).Multi-factorLogisticregressionanalysiswasusedtoanalyzeinfluencingfactorsofcoronaryin-stentrestenosis.

与无再狭窄组比较,再狭窄组血清总胆红素水平[(14.02±6.76)μmol/L比(10.90±4.51)μmol/L]显著降低、支架直径[(3.06±0.86)mm比(2.87±0.44)mm]显著减小,P均0.01。多因素Logistic回归分析结果显示,血糖水平是冠状动脉支架术后再狭窄的独立危险因素(OR=2.,P=0.),而支架直径和血清总胆红素水平是其保护因素(OR=0.,0.,P=0.,0.)。

Comparedwithnon-restenosisgroup,thereweresignificantreductionsinserumleveloftotalbilirubin[(14.02±6.76)μmol/Lvs.(10.90±4.51)μmol/L]andstentdiameter[(3.06±0.86)mmvs.(2.87±0.44)mm]inrestenosisgroup,P0.01both.Multi-factorLogisticregressionanalysisindicatedthatbloodglucoselevelwasindependentriskfactorforrestenosisaftercoronaryarterystentimplantation(OR=2.,P=0.),whilestentdiameterandserumleveloftotalbilirubinwereitsprotectivefactors(OR=0.,0.,P=0.,0.).

从中可知血糖水平是冠状动脉支架内再狭窄的危险因素,支架直径和血清总胆红素水平是其保护因素。

Bloodglucoselevelisanindependentriskfactorforrestenosisaftercoronaryarterystentimplantation,whilestentdiameterandserumleveloftotalbilirubinareitsprotectivefactors.

来源心肺预防与康复

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